The present invention is drawn to methods for photodynamic therapy of a target cell, target tissue or target composition in a mammalian subject, using a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. The device includes a marker housing having a base and a cover to enclose the moveable socket of a fishing rod thereby preventing removal of the fishing reel from the fishing rod. The first subsystem, called a video server, streams video to video on demand subscribers through the cable television network. In one case, a playback volume at which the audio content is being rendered may be adjusted. 004 lbream per side and drying the coated film to set the coating. The system also includes processes for collecting relevant information for storage within the data store and processes for harvesting information from detected social engineering attacks for entry into the data store and seeding of the collection processes.