A toilet seat device includes an annular base member rotatably attached onto a toilet bowl, and a board for safely and stably supporting children on the annular base member. This method includes forming a cut section extending in a radial direction in each of the core steel plates in the progressive press process so that the cut section is located in only one place in a circumferential direction. A first oxygen sensor generates a first oxygen signal. Heat is transferred from the heat sink on the portable computer to the guide protrusion on the guide bar. In certain embodiments, the peptide is modified at the amino-terminus, the carboxy-terminus, or both. The MLSE operations performed at the soft trellis are thereby of reduced complexity levels.