An object of the present invention is to provide a technology for preventing wrinkles on metal foils such as nickel, tin, cobalt, chromium and iron from being generated in order to facilitate their handling. The NGF antagonist may be an anti-NGF antibody that is capable of binding hNGF. The dispenser includes a drive mechanism that further includes an actuator for actuating the dispenser; and a drive wheel, wherein the drive wheel further includes mechanical means for engaging the actuator. The unidirectional and bidirectional OSC BBs provide a means for OAM&P functionality to the optical network.