A method and apparatus for compressing data is described. The invention provides methyl ester solvents suitable for use in the development of photopolymer printing plates. The present invention further relates to methods of using the bioactive compositions of the present invention, including, for example, methods for inhibiting inflammatory activity in skin tissue of a mammal, for protecting skin tissue of a mammal from ultraviolet light-induced damage, and for normalizing skin disorders in skin tissue of a mammal. The ICG’s gated clock output may be coupled to the scan latch clock input, which may hold its data output at a fixed level in response to ICG’s gated clock output being inhibited from changing during the scan capture operation.