Described herein are methods and systems for applying extremely low duty-cycle stimulation sufficient to treat chronic inflammation. 9% by weight of compounds having structural elements in which the free valencies on the oxygen atom and on the nitrogen atom may be combined to form a five-, six- or seven-membered ring and the benzene ring may also bear substituents at one or more of the free positions, and from 0. A control message with a request for confirmation of a process verifying the authorization of use andor payment process is transmitted to the mobile telephone terminal. In order to avoid such a detrimental loss of signal contribution, it is proposed to provide a central electrode 35 in the central bore 36 such that secondary electrons that approach the bore are driven aside towards the electron-sensitive detector region 48. A biopsy site marker applier of the system includes markings associated with different biopsy device configurations. The porosity of the substrate permits accumulation of particulate constituents of the exhaust stream without detracting from the engine performance due to backpressure.