A digital mixer system and method is disclosed. The strip-shaped substrate is a strip-shaped textile or a strip-shaped film. The first cardiac region is paced to maintain at least a minimum cardiac rate, and the second cardiac region is paced to maintain at least the minimum cardiac rate when a pace in the first cardiac region is inhibited. The safety reel of the present invention allows the quick and easy replacement of tubing. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer’s disease and schizophrenia, are also provided. By collapsing the reservoir containing the liquid, a user can break the membranes and propel the liquid and pill into his or her mouth to be swallowed.