The present invention relates to compounds useful as inhibitors of protein kinase. The apparatus, in an embodiment, includes an ozone generator connected to a scavenger and an ozone administrator via network of tubing and valves. A means for matching at least one extractor to the semistructured information to return a list of potential matches is also included. However, the coordinates of turns along the route as well as points along long stretches of road in the route are of particular interest. The method teaches bundling together a plurality of glass rods of specific physical, chemical, or optical properties and wherein the rod bundle is fused in a manner that maintains the cross-sectional composition and refractive-index profiles established by the position of the rods.