The present invention relates to a process of increasing the expression of TGF-1 by cells in a mammalian patient, comprising administering to the patient an effective amount of stressed mammalian blood cells, said stressed cells having been extracorporeally subjected to at least one stressor selected from oxidative stress and ultraviolet radiation. The dealer then turns up each of the cards sequentially from the two groups of the first deck, with the object being to attain an exact match between any or the cards of the two groups, and the reference card. In response to receiving the response to the plurality of test audio packets, the system activates a signal correction action when the value for the quality of service characteristic fails to meet a performance threshold. These tasks may include receiving data, or undertaking planning, or such other tasks as prescribed. Optionally, the cells can be induced to cease proliferation. Other embodiments include a metal bone plate which is held to bone by a metal bone screw and a nut of bondable material bonded to the plate to secure the connection; a piece of bondable material bonded to a metal prosthesis to custom fit the prosthesis; and a surgical implant custom formed by bonding together a plurality of discrete elements one or more of which is bondable.