Pesticidal compositions which are environmentally safe, consisting essentially of a minimum risk pesticide in combination with one or more inert ingredients are disclosed. The reagent comprises heparin and substrate coated with the analyte-counterpart. Also the present invention relates to a method of treating diabetes type II, obesity and to regulate the appetite of mammals. Connecting pins are inserted into the connecting pin hole 114. Based on the quantity of deviation of this detected pattern, the quantity of printing positional deviation of the color to be measured is detected.