A decoder conceals errors in a coded image comprised of a stream of macroblocks by examining each macroblock for pixel errors. A clamping through-bore extends between, and opens out to, the first and second end faces. The water diversion body is rotatably connected to the fixed unit inside. The invention further provides method to identify variations in a protein biosynthetic process that alter the solubility of a target protein and methods to screen an expression library of recombinant clones to identify clones that express soluble proteins. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.