This invention relates to the treatment of a patient’s lung, for example, a lung exhibiting chronic obstructive pulmonary disease and in particular to methods and devices for affecting lung volume reduction, preferably for achieving acute or immediate lung volume reduction following treatment. The fluid inlet includes a nozzle that defines a first plurality of orifices and a second plurality of orifices having a larger diameter than the first plurality of orifices. The monitoring assembly further includes a sensor assembly at least partially disposed in the mass measurement chamber, the sensor assembly adapted to measure a mass of the fluid disposed in the mass measurement chamber. A guide plate of the take-up structure is movably connected with a bracket of the lower housing, whereby by means of changing the position of the guide plate relative to the second lower rotary shaft, the take-up timing can be adjusted. In a preferred embodiment, the carrier is 4, 7, 10, 13, 16, 19 docosahexa-enoic acid and the drug is dopamine. Further disclosed is an electrochemical analysis system which includes the probe and a support plate operable to retain a plurality of samples of test material thereupon.