Briefly, in accordance with one or more embodiments, an optical relay comprises a partially-reflective-coated Fresnel lens or similar low-profile lens such as a diffractive lens or a holographic lens having a first index of refraction and a filler medium having a second index of refraction and being disposed adjacent to the Fresnel lens. Methods for evaluating Metabolomic databases for biochemical markers that correlate with outcome of a disease, allow monitoring of therapy and direct therapy. A button of the front frame folding assembly is pressed with single hand to detach a second slider of the front frame from a roller to make the front frame rotatable and folding to the rear frame. The present invention also decodes the compressed digital signal.