A microarrayer apparatus for constructing arrays of biological material from donor cores obtained from at least one donor block and placing the donor cores in an embedding medium carried by at least one recipient block. The aerogels are produced by forming a polymer gel structure within a solvent from a olefin or dicyclopentadiene monomer 5 via Ring Opening Metathesis Polymerization reactions, followed by supercritical drying to remove the solvent from the aerogel. A method for orienting plates using the label and a system of labeling are also provided. In a second stage, the initiator is added, and in a third stage, the remainder or full amount of monomer are added directly or in emulsion form in the presence of further water and, where appropriate, further dispersing assistant or other auxiliaries. By identifying said mutation, the efficacy of the EGFR-TKI treatment and the progression-free survival of said object after treatment can be estimated. Successive mixing and kneading disks make an angle of crest misalignment which is not integrally contained in 360\xb0.