A computerized method enables a preferred orthodontic appliance to be used in real-life orthodontic treatment of a patient to be selected. This system comprises a Personal Security Device 75 and another device 105 which is in functional communication with said Personal Security Device. This compound also may be used to treat autoimmune disorders and inflammatory diseases in humans as well as renal osteodystrophy and obesity. A flange portion 2 is provided around the tubular main body 1 at a portion spaced from the lower end of the notch 3. The inverse of T2, as used in this equation is an estimation defined by first creating an intermediate matrix {hacek over } of equal size as T2.