A transimpedance amplifier having adjustment for optical distortion in an optical communication link. A dual mode indication system of the present invention provides two different types of navigation information in a single device presentation configuration that is efficient and effective. During time intervals while in the standby mode, the voltage supplied to a subset of said plurality of circuits is increased to a level necessary for a refresh function associated with said subset of said plurality of circuits and then it is reduced upon completion of said refresh function. In another embodiment, bird, animal or human manure is added to the kiln so that gaseous reducing agents can be released by the manure and combine with certain noxious gases generated during the clinker production, to thereby reduce the noxious gas output. AGP-3R-related proteins of the invention may be membrane-associated or in soluble form, recombinantly produced or isolated after natural production.