The present invention relates to novel phosphonic acids derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors. Ullage above the ink in the ink reservoir is coupled with ullage above the ink in the ink tube. 2 or less can secure fluidity of the mixture with a resin, even when it is produced by milling to have particles of indefinite shape, and give a composite dielectric material of excellent dielectric properties. The musical score data after the velocity is corrected is played by the MIDI sound generator, amplifier and speaker. The multiplexer multiplexes the data from all its input channels and then relays the data to the demultiplexer. A write gap spacer is positioned between the front bar and each of the plurality of front blocks, and a write gap element comprising write gaps couples the front bar to each front block across the write gap spacer.