An actuator adapted to adjust the profile of a carrier supporting a bar relative to a lapping surface. The UE device’s VCC operational mode is provided to be selectably alterable responsive to user input. The invention comprises use of sRAGE prepared by the methods of the invention for treatment of AGE-related syndromes including complications associated with atherosclerosis, diabetes, kidney failure, systemic lupus nephritis or inflammatory lupus nephritis, amyloidoses, Alzheimer’s disease, cancer, inflammation, and erectile dysfunction. The suitability of the rolling bearing for high rotational speeds and the stiffness of the rolling bearing are increased as a result.