A hydrogel is provided in which varying ratios of acrylyol-modified dextran molecules and acrylyol-modified hyaluronan products are cross-linked to form a hydrogel conjugate. A heat sink is arranged below the nuts and an insulating plate is sandwiched in close contact with the nuts and the heat sink. The device further includes an actuator, the actuator including a handle case having a proximal portion for gripping and a distal portion including means for attaching the actuator to a cartridge. According to the invention, the radial openings in valve housing are provided as windows having a rectangular cross section. The receiving mechanism contacts the container and receives the signal from the fluid in the container.