A light-emitting device is provided having an anode, a cathode, and a light-emitting material contacting and separating the cathode and anode. A solid state image pickup device has pixels that are arranged in two dimensions and are divided into image pickup areas. The compliance zone designator transmits an ultrasound signal to establish the compliance zone. The present invention is further directed to a method for treating fibrosis in a subject in need of treatment, comprising administering to the subject an amount of ebaf or an ebaf analogue effective to treat the fibrosis. At least one of the curved sections may comprise an arc of greater than about 180\xb0.