The present invention relates generally to methods of preventing or treating toxicities of the skin, hair, andor nails, which are associated with administration of one or more vascular endothelial growth factor receptor inhibitors, with light-emitting diode photomodulation treatment, either alone or in combination with other agents. It provides the user the ability to control the video capturing direction of the handheld video camera from a distance away. A CPU selects either one of a normal operation sequence or a power-saving operation sequence in accordance with the type of battery upon carrying out an operation mode. The mobile appliance can be equipped with a compass which can be electronic and which allows a user to be shown the direction of travel in order to reach the destination. The apparatus may also allow multiple sets of dice betting using a plurality of physical sets of dice and an electronic betting terminal. The intrinsic semiconductor layer includes an amorphous semiconductor layer and a crystalline semiconductor layer including a plurality of crystals.