Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided herein. Application of different stimuli causes the actuator to bend andor twist. The method further comprises sensing an engine coolant temperature of the vehicle at a first time period, activating the preheating strategy to heat the engine if the engine coolant temperature is lower than the minimum engine temperature. A video camera is arranged to cover the diameter of a log on the carriage and to view the laser line projections and control the speed of the power drive motor of the carriage, to provide optimum speed of movement of the log through the band saw.