An enzyme detection method includes forming a caged substrate; releasing an uncaged substrate by cleaving a caging molecule from the caged substrate; and emitting a light emission from a Bioluminescence Resonance Energy Transfer luminescent nanocrystal conjugate reacting with the uncaged substrate. In this step, the distance for which each triangle is projected decreases as the thickness of the object at the position corresponding to the triangle decreases. Each contact includes a soldering portion, two retaining portions, and a curved portion connecting between the two retaining portions. The ADC lookahead pipeline uses open-loop residue amplifiers. A system according to one embodiment includes a controller for controlling a drive mechanism, the controller being configured to perform the foregoing method. Dies can thereby be replaced quickly and easily without spilling any coolant.