A method for enabling voice driven interactions among multiple interactive voice response systems begins by receiving a telephone call from a user of a first IVR system to begin a transaction; and, automatically contacting, by the first IVR system, at least one additional IVR system. A sub-frame juxtaposed below the front side member abuts on the member rear half section. The first request is associated with a first data structure that specifies a first access method. The invention further provides method to identify variations in a protein biosynthetic process that alter the solubility of a target protein and methods to screen an expression library of recombinant clones to identify clones that express soluble proteins.