A variable-resistance material memory device includes a container conductor disposed over an epitaxial semiconductive prominence that is coupled to a VRMM. The apparatus includes a supply of compressed dry air through the tubing with individual dispersion nozzles. The core material can be a relatively low melting point metal, plastic or polymer. A controller that calculates a weighting coefficient for the output of each filter. Also disclosed herein are methods using the micropores and microfluidic devices comprising the micropores. Compounds of the present invention are useful for inhibiting CARM1 activity.