Systems and methods employ a layer having a pattern that provides multiple discrete guided mode resonances for respective couplings of separated wavelengths into the layer. The control module directs a pulse generator to apply pre-conditioning pulses to subject tissue cells in a pre-conditioning zone to electroporation, the pre-conditioning zone being smaller than a target ablation zone. The fiber band is supplied by a fiber band delivery system that is associated with the wrist and that is characterized by a capability to twist the fiber band in two stages about the yaw axis or the roll axis.