A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The culturing device comprises a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and a fluid distribution means at the inlet and the exit of the growth areas. In another aspect, a composition design component interacts with a user to build andor modify services based upon identified aspect of business processes to be implemented by services, wherein the component design component recommends candidate services that can implement the aspects of the business processes from the group of services based upon information derived from the system knowledge. Each entry in the fragment cache contains data indicating where the glyph data for the glyphs of the fragment are stored in the glyph caches. Each customer record entry is associated with a unique customer identifier. The invention also includes a heat exchanger having a number of such fluid pipes.