1460774230-f2e60540-e981-40c8-b2e2-3fafe12d14d5

The present invention is directed to pyrazolopyrimidine derivatives of formula wherein the substituents are defined herein, which are useful as kinase inhibitors and as such are useful for affecting angiogenesis and diseases and conditions associated with angiogenesis. Hydrolysis of these linkages on oligosaccharides produces substrates for further N-glycan processing in the secretory pathway. Words are then filtered from the texts in which their occurrence ratios are substantially higher than their occurrence ratios in at least one of the other texts, to generate a clean text. A conveyor belt is wound about the belt roller. In the preferred design, the circuit also detects control voltages for solenoid locks and produces suitable control signals for a motor actuator.