A remote-controlled circuit breaker system, comprising a single voltage input connector for receiving current from an external power supply, at least two pole assemblies each including a trip mechanism, and a trip crossbar. The sealing mechanism engages the base plate to diametrically expand when the variable distance between the top plate and the bottom plate is reduced. They also inhibit in a preventive manner the pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure. Once the tension member is tensioned, the first and second connector pieces are pulled into a locking engagement thereby securing the catheter tube in the locked configuration. The present invention for the first time defines a direct functional role for p-preDC in HSC engraftment and will have a significant impact on strategies to design effective facilitating cell-based therapies for transplantation.