Machine for opening pistachios, a reservoir containing pistachios, a device for opening pistachios, and a device for supplying pistachios from the container to the opening device. The lid handling assembly comprises a pair of ramps onto which a lid is lifted by a lifting mechanism configured to handle overhanging lids or non-overhanging lids as required. The polymeric structures include an area that is attached to the substrate and a detached area that is not attached to a surface of a substrate. Further, patient response data is also input to the process controller, thereby enabling extremely fast and accurate test analysis with minimal effort by the device operator.