The claimed subject matter provides a system andor method that facilitates optimizing a controller within an industrial automation environment. The turned portion 43 is provided with a contact portion 43a contacting a pin of a PGA package on a surface of the turned portion 43 not facing the base portion 41. In some embodiments, the mTOR inhibitor is sirolimus and the tyrosine kinase inhibitor is imatinib. The controller arrangement also includes a force sensing infrared LED and photodiode assembly configured to detect when the nib contacts the page so that the sensor assembly is only activated when the nib is in contact with said page, and an accelerometer configured to allow the controller to sense motion without reference to the location tags. The sensor is manufactured of at least three individually processed wafers which are finally joined together and form a top part, a midsection and a bottom part.