The invention features methods of high throughput screening of candidate drug agents and rapid identification of drug targets by examining induction of the stress response in a host cell, e. For drug delivery, the SSP system includes an active drug ingredient and a matrix of perforator material that biodegrades or dissolves quickly upon contact with a patient’s body. Operating angle command values of two points in front and back at which the intake air amount is decreased by a predetermined amount with respect to the value that is judged to be a maximum value of the intake air amount when the operating angle is kept changing, are acquired.