The present invention discloses method and apparatus for regulating optimum flow of semen and separating motile sperms. Methods of use for treating angiogenesis or cytokine related disorders, and pharmaceutical compositions of these compounds are disclosed. If the print data is a print instruction other than the above-mentioned instruction, the printer determines whether the print data is a page to be overlaid on form data. In a specific embodiment, negatively charged carriers generated by optical absorption by the structured material are preferentially separated into the electron transportinghole blocking material. The protrusion is supported by one or both of the insertion opening and the shoulder defining opening.