The invention relates to a method for activating human-derived antigen-presenting cells by in vitro cultivation with at least one of the glycoside compounds represented by formula or salts thereof preferred example: -1–2-hexacosanoylamino-3,4-octadecanediol, and to human antigen-presenting cells activated by the method. The engine cooling system includes a cylinder head including an integrated exhaust manifold that directs exhaust gases to an exhaust outlet port and a coolant passage surrounding the exhaust manifold. Accordingly, the mobile node can promptly acquire an IP address without an additional request. The system and method convert both types of content into, at least, blog information and blog data.