A method of manufacture of an integrated circuit packaging system includes: providing a substrate; attaching a device to the substrate; providing interconnects on the substrate; and forming a flexible tape substantially conformal to the device and contacting the interconnects. The concentration of the contrast enhancement agents is measured by the concentration sensor during injection of the medium into the patient to assist in controlling the delivery system andor an imaging procedure. A rotation of the lifter link in a rear direction is restrained by a loosely fitted portion of the stopper link contacting an inner circumferential part of the long hole. When detecting an optical signal, the photodiode generates a current signal output from the second terminal.