An optical fiber comprises a flame retardant tight-buffer coating. In the bi-directional optical assembly, the first transmitting optical subassembly and the receiving optical subassembly are optically coupled with the optical fiber via the inner housing. This makes it possible to immediately obtain an anti-shake effect even if the playback mode is switched to the image capturing mode. Methods and compositions for the treatment of cancer associated with expression of IMP3 are also provided. The water reservoir is pivotally mounted on the base about a vertical axis to occupy at least one closed position and at least one extended position.