A foaming cement, cooperates with the steel member, forms the fender structure, which could solely resist the load in horizontal or vertical direction, or cooperate with the columniation. This connection is protected by an elastic socket, such as a sealing bellows, connecting the shafts. Increased cGMP results in activation of protein kinase G, which then is retrogradely transported along the axon to the neuron cell body, where it phosphorylates MAPKerk.