Disclosed is an electrochemical sensor for the determination of analytes in body fluids, e. The nanophase aluminum alloy duct is fabricated by extruding a billet formed by a process of cryogenic milling the alloy, followed by out-gassing, then hot isostatic pressing. With the estimated complexity measure of the current picture, an instantaneous complexity measure for the set of consecutive pictures is updated. Polymers and resists of the invention can exhibit substantial resistance to plasma etchants.