A Toroid Cavity Detector is provided for implementing nuclear magnetic resonance studies of chemical reactions under conditions of high pressures and temperatures. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods. The boost converter increases the voltage level above that provided by the power source while maintaining current at or near the level sensed by the current sensor, and while also maintaining a charge on the energy supply capacitors.