A working end of a surgical instrument that carries first and second jaws for delivering energy to tissue. The transfer step is arranged to transfer into a reaction chamber a holder that supports the substrates at intervals. The mask member has openings at positions corresponding to the light-emitting diodes which are placed inside the respective openings. A boundary between the first liquid repellent film and the second liquid repellent film is on a circle which is concentric with a circle forming a circumference of the ejecting port of the nozzle. As used herein, the term \u201ckernel-based classifier\u201d refers to a classifier where a mapping function has been used to map the original training data to a higher dimensional space where the classification task may be easier. At this time, a loss in the mechanical energy caused until it is transferred to the power generation unit GU by the slide member 10 is smaller than that caused as a result of the pressing operation of the cleansing button MB2.