Methods and systems for proactively processing errors in customs data transmitted to a customs broker are disclosed. The core circuitry is powered by a first supply voltage during use, and comprises a control circuit configured to generate a pull up control signal, a pull down control signal, and at least one reference voltage. Further provided are pharmaceutical compositions and kits comprising the therapeutic agents of the invention. The visible light is light configured to have a wavelength so as to be able to prevent the phosphor of the phosphor paste from being excited and emitting light and reflected by a liquid surface of the phosphor paste to produce reflected light.