The process of System Reconstruction is used to integrate sequence data, clinical data, experimental data, and literature into functional models of disease pathways. The flavor syrup injector injects flavor syrup at an angle towards the longitudinal axis of the nozzle exit orifice such that the nozzle exit orifice does not come in contact with the syrup, avoiding color and flavor contamination of other dispensed beverages. The vessel further includes a working deck supported by the hull of the vessel which covers at least a portion of the moonpool to allow the assembly of a riser string. The assembly further comprises a locking mechanism cooperating with the prongs to secure the adapter assembly in place. Also disclosed are therapeutic methods for using the cysteine variants of the invention. Such packets are particularly suited to an electrostatic trap because the FWHM of each packet’s TOF distribution is less than the period of oscillation of those ions in the electrostatic trap.