A method is provided for identifying complexes between a transcription factor and another protein, such as another different transcription factor. A plurality of data fields is specified for copying from the at least one primary database. The second laser region is used for generating a second optical spectrum having a second laser mode channel space. At least one of the needle trajectories is oblique to at least one other of the planned needle trajectories. The evolution of the pressure measured in step D is analyzed as a function of time, to determine whether the check valve has been opened. Each flange is substantially an isosceles trapezoid and comprises a top surface, a weakened base and two inwardly pointing sides extending from each end of the weakened base.