This invention provides metabolites of SARM compounds including inter alia glucuronidated metabolites and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, muscle wasting disease andor disorder, a bone related disease andor disorder, metabolic syndrome, diabetes and associated diseases, and others. The apparatus for monitoring includes: a pair of bipolar transistors and a first non-linear isolation element. Furthermore, a robustness of the proposed FQ channel estimation scheme to accommodate errors in a channel delay profile and to errors in a channel power profile is demonstrated through simulations. The automatic gain control design is intended to quickly acquire new incoming information in a wireless signal.