A three-dimensional electronic program guide is displayed as multiple two-dimensional areas within a three-dimensional television viewing environment. One of the two reacting groups is a substitute group and the other is a leaving group; and the biomolecules are covalently bonded to the solid support via a chemical ligation reaction between the two reacting groups. A second plurality of optical fibers is connected to a second receptacle using the alignment system to align the second plurality of optical fibers in the second receptacle.