Bisaryl-sulfonamide compounds having the formulawherein Ar, R1, R2, L, B, W, X, Y, and Z, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPAR\u03b3 or PPAR\u03b4. Also included is a system for transmitting at least one alarm and a database including, for each one of at least one predetermined reference activity, an occurrence of which is likely to generate acoustic waves in the monitoring area, reference characteristics relating to said predetermined reference activity. 11 signal by means of said signal processing unit and RF modulationdemodulation unit, and then down-converted from 2. According to another embodiment, the aqueous liquid composition contains Ag ions and the at least one reducing agent is omitted. An intermediate layer of material is then provided that covers the irregular face of the irregular layer, the intermediate layer providing a substantially flat surface.