A method of forming a linear polarization-maintaining optical fiber for use in an amplifier, the method comprising the steps of:. The method utilizes a sophisticated pre-analysis step to comprehend the function-call structure, the function-call layout, and the entire function call graph of the program, in order to determine strategic points in the program for changing the program. They arm also useful in prolonging survival of islet tissue transplanted into a mammal. Control circuitry configures the device for operation to prevent sudden cardiac death after programming the two or less programmable parameters and enabling the therapy OnOff parameter. Preferably, the vehicle preferences may be input by the operator into the portable handheld computing device.