A closure device for closing a puncture wound has a distal section that can be placed against the interior wall of a vessel and a proximal section that bunches in the tissue tract to close the wound. The active current modulator is operable to detect a negative current in the low-side switch of the buck voltage regulator circuit during a light mode operation. The apparatus can include at least one heat source configured to heat the fuser surface. The group of memory cells is erased, following soft-programming, resulting in a reduced threshold voltage distribution associated with the group of memory cells. 01 and about 5 bar; and a weight hourly space velocity of from about 0.