The present invention relates to methods for treatment of nerve cell death and neurodegenerative diseases. To form the substructure, a sheet of conductive material having exposed first and second surfaces is provided. For example, the external defibrillator may prompt the user to visually inspect the patient’s chest for signs that an IMD was implanted, such as a scar or raised portion of skin near the patient’s clavicles. The light receiving portion receives the light from the light emitting portion. A phase andor amplitude for at least one of the received WCDMA signals may be adjusted utilizing the estimated complex phase and amplitude.