HDAC inhibitor of the general formula exhibits strong inhibitory activity against various subtype HDACs. As the frame count is reduced, the amount of detected secondary electrons decreases, so that a probe current amount is increased to emit an increased amount of detected secondary electrons. According to an aspect of the invention, the treating element is capable of multiple movements from a first closed position, to an open position, to a second closed position and back to the first closed position via a single controller with a single linear movement. Certain of the keys have up to three different functions, depending upon whether the keyboard is in QWERTY mode, Dvorak mode, or numeric keypad mode. A sensor scans the coded information and relays it to a master control unit that controls the operation of the various sections. The sand control screen inside the perforated shroud can be an expandable-screen type screen.