An object is to provide a novel material having a bipolar property. A plurality of primitives are categorized into a first group of primitives that are to be displayed on a display and a second group of primitives that are not to be displayed thereon, by an XYZ clipping section, a Z testing section, and a stencil testing section, according to the data about the plurality of primitives in a primitive buffer. The compositions may also cause less vascular irritation compared to the same formulation of cytotoxic compound without cyclodextrin when administered intravenously without extravasation.